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Introduction
Perfidi is a set of parametrized families of pulse sequence preambles, applicable to almost all pre-existent NMR pulse sequences, whose effect is that of a high / low / band pass filter on the signals arising from different sample components according to their longitudinal relaxation rates R1 (or, alternatively, relaxation times T1).
The concept of PERFIDI was developed jointly by Stanislav Sykora (Extra Byte) and Paola Fantazzini (Physics Department and DICMA MRPM Lab of the University of Bologna) and was patented by the University (who is the owner of the patent) and the Authors.
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News and Events
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| 2007, Oct.26 |
Oral presentation at the annual meeting of the Società Italiana di Fisica (SIF 2007, October 24-28, Pisa, Italy). Click here for the presentation title, abstract, and slides. In italiano.
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| 2006, Nov.20 |
An article based on the Conference talk was accepted for publication in Magnetic Resonance Imaging, Vol.25, pp.529-532 (2007). Its title and Abstract are listed in the Documentation Section (the text of the paper itself is presently subject to the Journal's copyright).
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| 2006, Sept.20 |
Poster presentation of PERFIDI at the XXXVI National Congress on Magnetic Resonance of GIDRM, held September 20-23, 2006, in Salerno (Italy).
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| 2006, Sept.14 |
Presentation of PERFIDI at the 8-th International Conference on Magnetic Resonance in Porous Media (MRPM8) held September 10-14, 2006, in Bologna, Italy.
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| 2006, Sept.1 |
Application for the European Patent by University of Bologna and the Authors. The international application number is PCT/IB2006/001839.
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| 2005, July 1 |
Registration of the Italian Patent number BO2005A000445 by the University of Bologna and the Authors.
Start of 18 months confidential period.
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Documentation
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| 2007, Oct.26 |
Oral presentation by V.Bortolotti, P.Fantazzini, and S.Sykora at the annual meeting of the Società Italiana di Fisica. In italiano.
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| 2006, Nov.20 |
Article PERFIDI: Parametrically Enabled Relaxation Filters with Double and multiple Inversion
by Sykora S, Bortolotti V., Fantazzini P., Magn.Reson.Imaging, 25, pp.529-532 (2007).
Abstract : We present a novel approach to the NMR / MRI analysis of complex samples with a non-trivial distribution of longitudinal relaxation rates R1. The method, denominated PERFIDI, aims at separating signals arising from components with different R1's prior to actual data acquisition. Given any standard NMR / MRI pulse sequence, by itself insensitive to differences in R1's, it can be combined with a PERFIDI preamble which functions as a preliminary R1 filter and confers on the original technique sensitivity to the R1 dimension. The article states the principles of the approach, including the way of accounting for instrumental imperfections, and shows how to build PERFIDI filters with specific filter profile functions. Using terms borrowed from electronics, these are classified as low-pass, high-pass and band-pass types. Also included are an experimental verification example and a discussion of potential applications of PERFIDI in various NMR areas.
The article, subject to 2006 Copyright by Elsevier Inc, can be purchased online.
A draft version is available on one of the author's personal site.
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| 2006, Sept.20 |
Poster (PDF, 1144 kBytes) on New Universal NMR Sequences: PERFIDI and LAPSR
(by S.Sykora, E.Vacchelli, V.Bortolotti, P.Fantazzini).
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| 2006, Sept.14 |
Oral presentation of PERFIDI at the MRPM8 conference (with slides).
(by S.Sykora, V.Bortolotti, P.Fantazzini).
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| 2005, July 1 |
Abstract of the Italian patent, edited in English. Since the Abstract was published prior to the establishment of this domain, it appeared on the Extra Byte site.
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